My class got to go on a field trip last week.
I know! Field trips in a Master’s of Science program? How ridiculous!
It was awesome. We went to the Institute of Regenerative Cures in Sacramento.
I arrived early and waited out front with some classmates. Our tour guide arrived and we waited out front a little longer til everyone showed up.
While waiting the tour guide, who had designed the building we were about to go into, told us about his hobby, early television history!
After the primer on early television we entered the building and got a tour of one of the best facilities for practicing biology in existence right now.
The building itself was actually built a long time ago for the California state fair. It was the “women’s building.”
The brick exterior and columnaic entrance have stayed the same since the building was constructed to maintain the historical site. The interior has been heavily modified.
The building had no roof back in the day and was just an enclosure for a bunch of different events that you usually see at state fairs.
The building was sold to the University of California system. They slapped a roof on it, and used it to store records.
Our tour guide said that he was called in to turn it into a biology facility later on. Half the building is used for bio research while the other half is rented out to other companies.
The researchers in the Institute are working on a number of things. They researched a treatment for the “bubble boy disease” there. They’re working on using umbilical cords to create bone marrow for transplants, using Tal proteins to treat Huntington’s, creating HIV resistant cells, and helping people who can’t swallow to swallow are just a few of the things they work on there.
The tour guide also showed us the section that he was most proud of as he had designed it. A set of rooms for making the actual drugs and proteins to export to hospitals. Making the drugs requires extremely sterile technique to prevent giving someone who is already sick something that will make them worse. The rooms are designed to be extremely sterile.
To enter the rooms you pass through an airlock where you are required to cover every inch of your body in a disposable gown.
The airlock goes to a hallway with access to three separate clean rooms.
There is “negative pressure” in the rooms. That means that air is constantly entering the room from the top and going out the bottom. This is so that if any cells that are worked with in the rooms get into the air, they will be redirected to teh ground and sucked out through a grate in the wall instead of ending up in someone’s medicine.
The air is cleaned excessively to about 3000 times more clean than average air before entering the facility.
There is a lot of electrical equipment in the rooms that will require replacing eventually. To prevent electricians from having to gown up just to replace a lightbulb, all the eletricals are accessible from panels on the second story of the building.
It was pretty cool for a scientist like me to see the best possible place to do research in. The tour guide mentioned that he does tours of the interior of the super clean rooms for smaller groups. I might take him up on that at a later time!